In this study, the development of a low-cost electronic card-based medical device measuring and recording patient data was described via non-invasive methods. Both the descriptive statistical analysis and the regression model was performed from the pulse and galvanic skin response (GSR) from the volunteer' data. It is important to measure and record different data simultaneously with multiple sensors from the patient during the treatment, medical operation and care periods of the patients. The data measured from the designed device was evaluated for the patient's position, GSR, the respiration rate, the blood oxygen content, and the heart rate. The designed measurement and recording device were implemented with an embedded system-based microcontroller card. The designed device might provide for monitoring and recording data with led display, serial port, microSD card or internet of things.